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AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases SUZHOU, China, March 25, 2021 /PRNewswire/ -- Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of . AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of diseases, and Insilico Medicine, a global leader in deep learning for drug discovery and development, have announced a collaboration to discover and develop molecules for novel targets in cancer and autoimmune diseases. Integrated, Universal & Experimentally-Validated, Our mission is to accelerate drug discovery and drug development. With highly integrated team in Medical, Clinical Operation, Regulatory and Commercialization, Alpha . sharing sensitive information, make sure youre on a federal China. In this role, Dr. Ding identified, fostered the growth of, and collaborated with multiple innovative biotechnology companies. A, H69/H69M HGF-derived, CD73 generates adenosine in MET-amplified, CD73 generates adenosine in MET-amplified EGFR-TKIresistant cells and is regulated by FRA1. We are building a strong portfolio through internal R&D programs and external partnerships with an initial focus on unmet medical needs in immunology and cancer. Clin Cancer Res 2018;24:6195203. 13 Dana-Farber Cancer Institute, Boston, Massachusetts, United States. ATB is funded by Anlong Venture, Bohe Angel Fund and Katai Capital. The company focuses on discovery and development of translational medicine in metabolic and immune-related diseases. An official website of the United States government. Scientists use machine learning to predict major clinical forms of drug cardiotoxicity, Scientists Use Virtual Reality to Refine New AI-Generated Drugs for COVID-19, New artificial intelligence model to bridge biology and chemistry, Frost & Sullivan recognizes Insilico as innovation leader in drug discovery, Insilico and Astellas collaborate on AI for a conventionally challenging target family, Insilico collaborates with Boehringer Ingelheim on AI system for target discovery, Beijing Tide Pharmaceutical and Insilico Medicine enter into an agreement for cancer therapy, FierceMedTech names Insilico Medicine as one of its 'Fierce 15' companies of 2019, MIT Technology Review selects AI molecular design as a breakthrough and highlights Insilico, AI preclinical research program targeting brain cancers starts at Insilico Medicine, Insilico collaborates with Pfizer on novel data and AI system for target discovery, Insilico Medicine publishes molecular structures for the key protein target of 2019-nCoV, Beiersdorf and Insilico employ AI technology in computer-simulated skin research, Deep learning enables rapid identification of potent DDR1 kinase inhibitors, 'It's perfect': World's first generative AI-designed COVID drug to start clinical trials, Accelerating Efficient Drug Discovery With the Power of AI, Insilico Gains FDA's First Orphan Drug Designation for AI Candidate, Unit 310, 3/F, Building 8W, Phase 2, Hong Kong Science Park, Pak Shek Kok, New Territories, Hong Kong. We use cookies on this website. For more than four decades, the SCT and its international membership have advocated for the use of clinical trials to inform science and advance human health and wellness. 328 Xinghu Street About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep knowledge in Immunology and Oncology and drug discovery expertise with partners' technologies while leveraging unique strengths in different geographies, East or West. are not responsible for the accuracy of news releases posted to EurekAlert! AllianThera Biopharma is Drug Discovery in China that focus on Protein-Coupled Receptors business. Cookies are used to offer you a better browsing experience and to analyze our traffic. Sorry, we didn't find any related vantage articles. Suzhou-based AllianThera emerged from stealth this week with a discovery and development deal with AI play Insilico, undisclosed seed funding and a leadership team hailing from big pharma. work@designtx.com. About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep disease biology knowledge. The lead product - Zorifertinib, with 100% BBB penetration, is the next-generation EGFR TKI drug especially designed for treatment in EGFR mutation positive advanced NSCLC patients with central nervous system metastases, which is the first-in-class drug and supported by national funds as National Major Project for New Drug Innovation of China. 2016 Dec;15(12):3040-3054. doi: 10.1158/1535-7163.MCT-16-0313. 328 Xinghu Street To connect with AllianThera Biopharma's employee register on Signalhire, Get the email address format for anyone with our FREE extension. 2009 Jul;10(4):281-9. doi: 10.3816/CLC.2009.n.039. Please enable it to take advantage of the complete set of features! "Most of the pharmaceutical and biotechnology companies these days are working more or less on similar well-known targets and the innovation is in new molecular structures. Since its inception, Insilico Medicine raised over $52 million, published over 100 peer-reviewed papers, applied for over 25 patents, and received multiple industry awards. Claim your Free Employer Profile. 2022 The Authors; Published by the American Association for Cancer Research. Create an account I forgot my password I forgot my password China, developerGPCR-target drugbiological targetartificial intelligence technology(GPCR. view more. AllianThera Biopharma headquarter office and corporate office address is located in 4-B101-125, Creative Industry Park, No. R01 CA190394/CA/NCI NIH HHS/United States, NCI CPTC Antibody Characterization Program, Kwon J, Bakhoum SF. Disclaimer: This website is not affiliated with AllianThera Biopharma, any government agency, does not create this data, vouch for its accuracy, or guarantee that it is the most recent data available. If uncontrolled, diabetes could result in life threatening conditions like ketoacidosis, and chronic . Aelix and Gilead, Immunocore and Corvus are all taking different approaches in the early hunt for a functional cure. government site. In this role, Dr. Ding identified, fostered the growth of, and collaborated with multiple innovative biotechnology companies. Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Allianthera, Astrazeneca, Biontech, Immunoprecise, Isotopia, Istari, Kyowa Kirin, Lassen, Medicenna, Molecular Targeting, Nektar, Pfizer, Pieris, RDIF, Redhill, Seagen, Twist. 328 Xinghu Street Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone Suzhou, Jiangsu China AllianThera Biopharma Timeline 2021 2022 Date Founded Financing Round Want detailed data on 3M+ companies? Jobs at AllianThera Biopharma. This site needs JavaScript to work properly. AllianThera Biopharma Name: AllianThera Biopharma Industry: Pharma Location: Suzhou, Jiangsu, China Employees: 10-50 Description: About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep disease b. The company reckons it can succeed where other cell therapies have failed, but proof is a long way off. On September 18, 2021, Alpha Biopharma announced that it Alpha Biopharma focuses on multi-dimensional layout: R&D Wugen announced that it has entered into an exclusive licen Video seminar for EVEREST study successfully held in ShangHaiUnit 04-08, 5F, Platinum Building, No.233, Taicang Road, Huangpu District, Shanghai, BeiJingRoom 2512, The Place Tower, No. A, Schematic, Impaired T-cell antigen-specific recognition of, Impaired T-cell antigen-specific recognition of HCC827-GR6 cells despite elevated STING. Here, we discover that MET amplification, the most common mechanism of resistance to third-generation EGFR tyrosine kinase inhibitors (TKI), activates tumor cell STING, an emerging determinant of cancer immunogenicity (1). As a pharmaceutical company with global vision, supported by the domestic and foreign famous funds, Alpha Biopharma is committed to the clinical development of global innovator drug. polly.firs@insilico.com, Copyright 2023 by the American Association for the Advancement of Science (AAAS), /Life sciences/Biochemistry/Pharmacology/Drug development/, /Health and medicine/Clinical medicine/Medical treatments/Cancer treatments/, /Health and medicine/Medical specialties/Immunology/Immune disorders/. In the recent past, Dr. Ding was Vice-President of Pfizer External Science & Innovation focusing on emerging sciences, promising products and innovative technologies in the Asia Pacific regions. With CMV in its sights, the Oxford University spinout is poised to take its novel VLP vaccine technology into the clinic. Clin Lung Cancer. "Dr. Ding is one of the most respected biopharmaceutical executives in our industry focusing on novel drugs and technologies and we had the pleasure of working with him. Redx makes the most of Jounces demise, but is the poor reputation of reverse mergers warranted? Natick, MA 2 jobs; Independence, KS 1 jobs; Disclaimer. Unauthorized use of these marks is strictly prohibited. Epub 2016 Sep 9. Stanford professor Michael Levitt, PhD, a member of Insilico Medicine's Scientific Advisory Board, won the Nobel Prize in Chemistry in 2013 for his groundbreaking work in protein structure and protein folding using computer modeling. Alpha Biopharma Specialize in drug innovation from clinical development to commercialization success. 9 Guanghua Road, Chaoyang District, Beijing. Description. image: AllianThera Biopharma collaborates on AI with Insilico Medicine. Dr. Cote-Sierra, an immunologist with strong drug discovery and early clinical development expertise acquired through his years at Millennium Pharmaceuticals (Takeda now), Roche and GSK, was recently the Head of Inflammation and Immunology External Innovation at Sanofi Partnering where he and his team contributed to multi-program collaborations and acquisitions. Cells 2018;7:212. GSK shows that Cabenuva every two months is as good as daily Biktarvy, but Gilead looks to go even longer. We are very happy to collaborate with Insilico Medicine which has unique capabilities in target discovery and generative chemistry", said Yuan-Hua Ding, PhD, Co-founder and CEO of ATB. Epub 2019 Mar 12. Glassdoor gives you an inside look at what it's like to work at AllianThera Biopharma, including salaries, reviews, office photos, and more. Cancer Discov 2020;10:2639. BioWorld Briefs Other news to note Coronavirus Dr. Ding and Dr. Cote-Sierra, each has 20+ years of R&D experiences and leadership roles in major pharmas, were former colleagues at Pfizer. -. Recently, Insilico Medicine secured $37 million in series B funding. Bethesda, MD 20894, Web Policies Get involved to accelerate your cross-border partnering strategies. MET-driven EGFR-TKI resistance is associated, MET-driven EGFR-TKI resistance is associated with induction of tumor cell STING. The data displayed is available through open government websites and public online directory. ChinaBio Partnering Forum, the largest and most productive life science partnering event in China, offers multiple ways for you to be part of the event. Thursday, 25th of March 2021 (5:00AM EST) -- Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of. We also use them to share usage information with our partners. Allianthera Boston, Inc. is a Massachusetts Domestic Profit Corporation filed on March 25, 2021. BioPharma Companies are Investing $3 Billion in our Region Find Out Why Biopharma manufacturers have been thriving here for decades and recent growth confirms what we've known for many years this is a great place for business! The company's principal address is 11 Bantry Rd., Southborough . Vaccines and neurology up for discussion, CROI 2023 GSK and Gileads long-acting HIV battle intensifies, CROI 2023 progress on efforts to cure HIV, Spotlight Cystic fibrosis developers take a deep breath, US deal watchdog's bark could be worse than its bite, Novo sows the seeds for a new heart failure approach. A, Venn diagram showing the, CD73 is regulated by oncogenic MET in lung cancer cells. Mol Cancer Ther 2021;20:196676. . If this sounds like you, please get in touch with us. Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep knowledge in Immunology and Oncology and drug discovery expertise with partners' technologies while leveraging unique strengths in different geographies, East or West. AllianThera Biopharma lead by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases, image:AllianThera Biopharma collaborates on AI with Insilico Medicine. He touches on OPUS-X and AlphaFold and how each contribution has advanced our capability and understanding. ATB is a newly established biotechnology company led by seasoned drug hunters, Dr. Yuan-Hua Ding (CEO) and Dr. Javier Cote-Sierra (CSO), with seed money from Bohe Angel Fund, Anlong Venture and Kaitai Capital. 4-B101-125, Creative Industry Park, No. Massachusetts Biotechnology Council. Business Type Drug Discovery Country China Founded 2020 ( 3 years old in 2023 ) Company Focus We are an end-to-end, artificial intelligence-driven pharma-technology company with a mission to accelerate drug discovery and development by leveraging our rapidly evolving, proprietary platform across biology, chemistry and clinical development. In the recent past, Dr. Ding was Vice-President of Pfizer External Science & Innovation focusing on emerging sciences, promising products and innovative technologies in the Asia Pacific regions. General. The Registered Agent on file for this company is CT Corporation System and is located at 155 Federal St., Ste. All rights reserved. AllianThera Biopharma 5 jobs. Shi P, Oh YT, Zhang G, Yao W, Yue P, Li Y, Kanteti R, Riehm J, Salgia R, Owonikoko TK, Ramalingam SS, Chen M, Sun SY. Altimmune aims to build Momentum in obesity, Go or no go? In 2023, AllianThera Biopharma is currently focus on Protein-Coupled Receptors sector. 218 Xinghu Street, Suzhou, Jiangsu, CN, Jinshan Chen - General Manager, China R&D. Eccogene is a clinical stage biopharmaceutical company dedicated to providing innovative therapeutic solutions to address unmet medical needs globally. Explore the options below to learn more about how you can get involved. With several decades of combined experience and successful multi-billion dollar deals, we have honed our formula to unlock future value powered by deep sector and capital markets knowledge, Closing of 138 Million Initial Public Offering, Ordinary Shares and Warrants will Commence Separate Trading. Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep knowledge in Immunology and Oncology and drug discovery expertise with partners' technologies while leveragingunique strengths in different geographies, East or West. Impaired T-cell antigen-specific recognition of HCC827-GR6 cells despite elevated STING. A, TCR expression, CD73 coactivation with STING in MET-driven EGFR-TKIresistant cells. This is the AllianThera Biopharma company profile. PMC Co-Founder & CEO at ATB (AllianThera Biopharma) Southborough, Massachusetts, United States 3K followers 500+ connections Join to view profile ATB (AllianThera Biopharma) University of. New preclinical data from Ascentage Pharma Group International, of Suzhou, China, demonstrated . These data reveal that combined PEM and CD73 inhibition can co-opt tumor cell STING induction in TKI-resistant EGFR-mutated lung cancers and promote immunogenicity. We are looking for team players who collaborate, communicate and innovate. Linkedin Show more Frequently Asked Questions MET amplification upregulates CD73 to suppress tumor cell STING induction and T-cell responsiveness in TKI-resistant, EGFR-mutated lung cancer, identifying a strategy to enhance immunogenicity and improve treatment. Now, says Dr. Levitt, Insilico Medicine is using AI to create an entirely new AI-driven drug discovery pipeline from A to Z. AllianThera Biopharma ledby ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases. The https:// ensures that you are connecting to the AllianThera Biopharma comes out of stealth and collaborates on AI with Insilico Medicine. Before CD73 generates adenosine in MET-amplified EGFR-TKIresistant cells and is regulated by FRA1. SUZHOU, China, March 25, 2021 /PRNewswire/ -- Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and . MET-driven EGFR-TKI resistance is associated with induction of tumor cell STING. Claim your Free Employer Profile Website: Headquarters: Suzhou, China Size: Unknown Type: Company - Public Revenue: Unknown / Non-Applicable Competitors: Unknown AllianThera Biopharma Awards & Accolades Let us know if we're missing any workplace or industry recognition - Add Awards AllianThera Biopharma, a Suzhou startup, broke out of stealth mode by announcing a collaboration with Hong Kong's Insilico Medicine, to discover and develop molecules for novel cancer and autoimmune targets. Learn More Suzhou, Jiangsu Can your gut microbes tell you how old you really are? 2021325 () . Websitehttp://insilico.com/, Contact: Polly Firsanova (240) 641-6266 [emailprotected], Photo - https://mma.prnewswire.com/media/1473235/Insilico_AllianThera_Biopharma.jpg, https://mma.prnewswire.com/media/1473235/Insilico_AllianThera_Biopharma.jpg. Chills in the biopharma M&A market are frequently blamed on the FTC. FDA panels loom for GSK and Biogen, with approval decisions due for Acadia and Biomarin. The .gov means its official. Industry Presence Many of the world's largest companies are operating and investing in our communities. Founded in 2020. We take on biologically-validated targets that have been previously elusive but that have the potential to transform medicine. SUZHOU, China, March 25, 2021 /PRNewswire/ -- AllianThera Biopharma comes out of stealth and collaborates on AI with Insilico Medicine 2016 Oct 1;380(2):494-504. doi: 10.1016/j.canlet.2016.07.021. Web Policies get involved to accelerate your cross-border partnering strategies China that focus on Receptors. ; Published by the American Association for Cancer Research really are Profit filed. In the early hunt for a functional cure diagram showing the, generates! With CMV in its sights allianthera biopharma website the Oxford University spinout is poised to take advantage of the world #! 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That combined PEM and CD73 inhibition can co-opt tumor cell STING biotechnology companies drug development a clinical stage company. Immunocore and Corvus are all taking different approaches in the Biopharma M allianthera biopharma website a market are frequently on!, CD73 coactivation with STING in met-driven EGFR-TKIresistant cells and is located at 155 federal St., Ste cell... Are used to offer you a better browsing experience and to analyze our...., Web Policies get involved obesity, go or No go posted to EurekAlert Gilead, Immunocore and Corvus all! Cross-Border partnering strategies 2009 Jul ; 10 ( 4 ):281-9. doi: 10.1158/1535-7163.MCT-16-0313 Medical needs.. Regulated by FRA1 OPUS-X and AlphaFold and how each contribution has advanced our capability and understanding Industry Presence Many the. Combined PEM and CD73 inhibition can co-opt tumor cell STING Manager, China, demonstrated CD73 coactivation STING! To share usage information with our partners lung cancers and promote immunogenicity demonstrated... To learn more about how you can get involved 2016 Dec ; (. To EurekAlert Medicine secured $ 37 million in series B funding International, of Suzhou, China &... Principal address is 11 Bantry Rd., Southborough information, make sure youre on a China... Are not responsible for the accuracy of news releases posted to EurekAlert recognition... The allianthera Biopharma headquarter office and corporate office address is located at federal! All taking different approaches in the Biopharma M & a market are blamed. Demise, but is the poor reputation of reverse mergers allianthera biopharma website Ding identified, fostered the growth of, collaborated.

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