But its come to my attention that long term , My Mum had taken Alendronic for 10yrs after breaking her hip. sex. Hi everyone I thought my diziness and muscle ache and a light pain in my abdomen when i took Alendronic Acid was just me, now reading all the comments I can see it is a common theme. Tablets the gift that keeps giving, I have just had a DXA scan (following a wrist fracture) and it came back I have really bad osteoporosis. Ohh my Goodness thank you so much for your post. Sister told the doc she intends taking Boron. I hope you are ok. She sent me to a specialist for a second opinion and he said take it. Another problem that really concerns me is that my teeth feel rough, as though the surface is eroding. Now, the only exercise I get is pottering around my house or gently along my local high street. Whenever Ive mentioned it to my GP, its sort of brushed away. I guess my mouth has changed after a long time and it has not fitted properly for a while. My entire body jerked violently as if I was having an epileptic fit, but I was conscious throughout. Eventually, I Started Pilates and regular walking. I had open heart surgery at the end of December and didnt take the alendronate for a couple of weeks and coincidentally the swelling went I thought maybe it was caused by fluid build up due to my heart condition and thats why it was better. Cyclophosphamide (NSC-26271, Cytoxan) Monohydrate is a nitrogen mustard alkylating agent, it attaches the alkyl group to the guanine base of DNA, shown to crosslink DNA, causing strand breakage and . Dr David Brownstein has written, and talked on YouTube on this subject. Having read & researched online information regarding side effects I accepted that I needed to take the Prednisolone but was not comfortable with ADCAL 3D + Alendronic Acid & especially since my Vitamin D level was so good but was advised to take them taking into account my age of 73years. Im 61 and after a long history of fractures (mostly sports related) and a recent wrist fracture from a fall, I had a DXA scan and have Oseopenia. Took 1 pill of AA. reading all of your comments I will not be taking another one of theses tablets . This pain was far worse than the pain I experience withOsteoporosis! 74, fractured hip. My sister and I were diagnosed with Osteoproosis over 5 years ago and we have both been taking Alendronic Acid since. who told me it could be one of many things. Twin Research Aug 2005 Spine -2.9 Hip -1.3. Same here. 2 years after that I had a dexa test. I do wish you the very best Terms|Privacy, Research Forum for Enduring Sexual Dysfunction, https://info.mhra.gov.uk/drug-analysis-profiles/dap.html?drug=./UK_EXTERNAL/NONCOMBINED/UK_NON_000837661002.zip&agency=MHRA, https://www.druglawsuitsource.com/canada-fosamax-lawsuits-settled/. My legs and bottoms of feet, are so painful. I am aldo taking Calcio with vitamin-D Has anyone has this done ? I have been on Sertraline 70mg for a few years and as I have asthma my inhaler has been changed to Beclmetasome 100/6. 1800+ Cities. My 76yr old mom has taken 7 AA tablets and it has cause her hip, leg and groin pain that has become quite severe. She told me that all of these drugs, which is just a few, would cause me to have the same side effects. I also broke my hip, which made it even more difficult to do anything at all. I was told I had osteoporosis in 2004 and was put on Fosamax for about 6 months after which I was switched to Actonel. I reported the effect the drug had on me to the MHRA. I compared it with strontium ranelate, which was the drug my sister was taking, and the strontium appeared to have better results. Ive taken a covid test because these days thats what you do if you feel ill at all. For oral liquid medicine, use the dosing syringe to measure one unit (70 mg in 100 ml) of oral solution and take it once a week. If I apply pressure on my face in front of my ear, the ear pain lessens. I was diagnosed with Preliminary Billiary Cholongistis (PBC) in 2021 and am now informed I have osteopenia (May 2022); informed today that a prescription has been left at my chemist for Alendronic Acid to be taken once a week. I have had several extrane simpthoms after taking alendronic and had to give it up due to a dental treatment. Both the intermediate and the terminal half-lives exclusively represent the . Ive now been put on Risedronate and after just 24 hrs I ache all over and keep getting sharp pains everywhere , seriously thinking of stopping this as side effects are awful. Given ENEMA which got things moving but still having problems so was referred for COLONOSCOPY!! hi i broke my wrist last year and because of this I had a bone scan I was told I had osteoporosos in the Spine and hip im 57 and lead a active life ive on vitamin D daily and AA 70 ml weekly I took my one this morning a number of hours after taking this table I have had very bad stomach cramps and I have not left the bathroom and my head is bad. This led me to think I was in Seroxat withdrawal; so convinced, in fact, I was of this that I asked my doctor to contact GSK to see if they had changed the formulation in some way, as I had made no change to my dose. I also have arthritis in my thumbs. I drank 2 cups of coffee. Now my story is about alendronic acid and the slow but sure decline of my health and fitness. I was going through a traumatic time at age 45 yrs and was diagnosed with hypothyroidism, the menopause and depression all at the same time. I was left on Seroxat for 15 years and wonder if it is the reason I know have Neuropathy. GP is arranging for a bone scan . I expect only the shareholders are enthusiastic about it! I am on prednisolone for polymyalgia. For a once health, fit woman shes a frail person now who cant walk and has bladder/stomach problems. Im so sorry to hear your situation and how difficult things are for you. Ive just discovered that lack of it can be at the root of fatigue, depression, low body temperature, and many other issues. Took AA on Sunday and the next night I was in so much pain, I couldnt move. Fast forward to 2008. I took my first Alendronic acid tablet last Sunday. It begins as minor dental problems and can escalate to permanent jaw damage. Was taken into hospital and because I was taken alendronic they discharged me with 4 Tramadol pain was excruciating..Then I started knocking on doors ring any doctor who would listen no one listen. If I apply pressure to my temples, my headache lessens. Without the support of new bone tissues, your bones become more porous and fragile, making you prone to bone fractures. Put on strong doses of steroids. I would like to take an alternative to alendronic acid wuth some exercises for the spine. HELP! Ive not been offered another dexascan in four years but if this swelling goes down my GP can decide what he wants to do about treatment, if any. It could give you terrible side effects. Having read all the above I am going to see my doctor again about this drug. Some years later she was in terrible pain and her doctor wouldnt believe me when i said that i thought her hips were dying. No problems with my calcium + vitamin D levels when I started taking medication. She has stopped the tablets. 20 mile house bernadette 0533 929 10 81; best time to visit kodiak island info@reklamcnr.com; grateful dead from the vault box set caner@reklamcnr.com; athens high school basketball roster reklamcnr20@gmail.com My life coaching business came to nothing I am unable to work. My face had also experienced this and I have had swollen lips. I wont be taking it as I feel I may be able to find a natural alternative. She had breast cancer over 5 years ago and had a fall recently and broke her wrist. Hello Barbara I have osteopenia aged 58 and my sister has osteoporosis aged 65, she was prescribed Alendronic Acid with similar side effects. Yet we women know when something is not right we seek help only to be fobbed off by stupid replys from doctors only to get rid of us . I am 52 but had secondary cancer 18 months after my breast cancer. It belongs to a class of drugs called bisphosphonates. She is currently in a lot of pain when she walks. It is relevant at this point to say that my sister lives in Australia which has different prescribing criteria. 2023 The Heart & Brain. I thought that I had been duped, once, into taking a drug I probably didnt need for an illness I probably didnt have, a drug that damaged my health. But I Need to get an updated DEXA to see how things have progressed. If recommended to be taken twice a day, you should have it during lunchtime and dinnertime. Have been taking alendronic for 14 months now because I had a fall just over 15months ago and broke both knee caps, have been taking them once a week,but I find they make me dizzy so was thinking of stooping them,is this advisable? I too am very healthy woman 67, play golf dance swim walk, so I was upset to be told I had osteoporosis. Delighted to report Tum is behaving much better since giving up just hoping the other side effects ( Jaw and Teeth) dont show up unexpected! Alendronic acid contains an active ingredient, alendronate sodium, a bisphosphonate. Until this doctor expressed his surprise that I was taking it, and his opinion that it was possibly the cause of my problems, no one had ever raised any questions about it. She was given physiowhat a mistake that was.After fighting to get her x rayed, the doctor phoned her and said that I was right and she needed a hip replacement, her hips had crumbled away. I was prescribed AA 70mg one per week and took the first dose on Saturday which gave me such severe joint and muscle pain all over my body within 24-36 hours that I was barely able to walk or stand. I have been put on prednisone and even though my bones are ok I have been prescribed AA as prednisone destroys bones. Today is Wednesday! On research I found there has been class law suits against the manufacturer of this drug in Canada. With the agreement of my GP I have now stopped taking the tablets. There is a phrase called the patient financial profile which is the profit made from an illness or disease or condition without the patient either getting cured or dying. When I showed this to my GP, he said that is not correct and the book was wrong. It is a condition when you have fragile bones, making you prone to bone fractures or breaks from daily activities such as walking or standing. It is commonly prescribed to treat patients with bone issues like osteoporosis and Pagets disease. I didnt like what I saw. However, below are early signs of osteoporosis: Please see your doctor if your family has a history of osteoporosis to assess your risk. Hi just wondering how your getting on with the alendrolic acid? Your body naturally breaks down old bones and replaces them with new bone tissues to support your skeletal system throughout life. Gave up Alendronic Acid recently after a random chat with a friend! I should have been warned of this side affect. Hello Claire, I am 60 years old and very modern and active with and without my grandchildren. I hd bone density DXA scan scan in 2010 and was told i had http://www.ehealthme.com/cs/osteoporosis/drug+intolerance, http://www.ehealthme.com/cs/osteopenia/drug+intolerance, http://www.ehealthme.com/ds/fosamax/drug+intolerance. Singing, to my deep distress, is now out of the question, along with all the other active things I loved to do. Im very concerned and unsure what to do? I have recently been prescribed AA and, after researching this drug for its possible side effects and reading your stories, I really do not want to take it! I developed teeth probs just before diagnosis so treatment sounds scary if things are made worse by AA. I think she must have dislodged it, I also have something called GCA which can affect your jaw so I cant say which or if either has caused the problem. I am 55 years old female and took 1 70mg dose of Alendronic Acid 2 weeks ago after being diagnosed with osteoporosis after a Dexa scan. No tablet is worth taking if no quality of life. Its bad enough living with PBC and all that entails for the rest of my life, but to go through what all of you good people have gone through NO WAY DANNO! In addition, you should cut down on your alcohol intake, stop smoking, do strength training and supplement your body with calcium and vitamin D3, K2, and magnesium regularly. 3. However for the past couple of months the left lower side of my face has been continuously swollen and my family have finally noticed. I also have had a bone scan pre drugs so it would be interesting to find out when I can have another scan to see whether there is an improvement or at least no further loss apart from normal degeneration of bone. My wrists were swollen, aching. This was before I started checking and researching EVERY drug I was told I needed. Learn more. You should eat more foods that promote healthy bones. ). In 2002 I discovered via the internet that I wasnt desperately ill with an anxiety disorder that only Seroxat could fix. The effects of alendronic acid may occur after 1 month of taking it. Then, you can resume eating and drinking normally. Bisphosphonates can strengthen the bones and slow down further bone damage. User Reviews for Zoledronic acid to treat Osteoporosis. This was on top of my usual activity levels. Hi. Jan. Clinical particulars. I Have been taking Alendronic Acid Tablets for 11 months now. It will slow down the breakdown of bones and support the faster growth of new bones in your body. Hospital June 2014 Spine-2.5 Hip -0.9. Its such a dilemma. After 2 weeks of no bowel movement ended up at A&E!!! These drugs are pushed to the top of the prescribing line by big pharma. Thank you for all y9our input re: Alendronic Acid. I do have quite a high reading of osteoporosos but I feel I need to know what it really does to the body. My worry at the moment is that I need a new crown in my teeth and do not know if this permitted and if I go ahead will it affect the health of my gums. But I just couldnt describe it as you have. I feel so Ill, but after reading the comments regarding AA, Im not sure, if its the AA causing these problems, Im afraid to take my next one, on Thursday. Alendronic acid is generally safe for long-term use and stays in your body. Is it possible to just stop taking the tablets? Im considering ringing the hospital myself to see if I can have one done. My bloods were fairly normal although my Vit D was just within normal. The NHS Dentist has ben very negative and created time consuming visits which are difficult for me to arrange because I have decreasing mobility because of MS. No one my GP or the dentist recommended by my GP have given me no warning about the serious side effects of having dental extractions while taking Aldronic Acid. thanks for this site. Take one tablet of alendronic acid 70 mg weekly if youre prescribed brands like Fosamax and Fosavance. My specialist came back to me a month ago to tell me I should take AA from now on so I started taking the weekly pill 4 weeks ago. She said for the to call in on monday if there is no improvement. Once a week at the same time. Six hours later, left jaw joint tightness, nerves in teeth/jaw became sensitive (lasted a day), runny stools, dry mouth, calf cramps (at night). The whole remit of Western medicine is to treat symptoms without curing, so that long term profits can be made. I was put on alendronic acid weekly and vitamin d and calcium twice a day . From day one my tummy was not happy & after 8 weeks I suddenly became severely constipated (Literally overnight !!!) So if u are on adcal or calcium as well check out it isnt that causing any side effects. But the following is extract is certainly familiar; http://www.drugwatch.com/fosamax/osteonecrosis/, Fosamax is linked to osteonecrosis, or bone death, of the jaw. I asked how we would know if it wasnt working, and his reply was that it would be having an effect on my bones after six months and the next scan results would indicate an increased bone density, or not. These may increase the risk of damage to your jaw bone. Took dose 7, and on and off right hip aches, but now radiating to thigh. Withdrawal was so extreme that the longest I ever lasted off the drug was seven weeks, the worst of my life. Stop taking your next dose if you experience rash or hives, swelling of your face, lips, or tongue, and trouble breathing. Instead of the exercising I need and want to be doing, my muscles are weakening, my joints ache, my tendons burn and my bones are probably crumbling away. Many thanks, Diagnosed with myasthenia gravis in January and prescribed boat load of tablets. Due to cutbacks now prescribed unnamed Alendronic and feel absolutely ghastly. Please tell your doctor if youre pregnant or planning to before taking this drug. I was intrigued as my doctor had said specifically not to! My sister was recently told by her doctor that as she's been on it for over 5 years she should stop taking them for 3 years. I am 79 and took my first Allendronic tablet last Weds. I am diary intolerant. I suffer with Reaumatoid Athritis, so put the pain down to this, plus the osteoporosis. My mother is 83 and has been on this drug for over twenty years with only one bone scan. There is a fine balance struck in order to treat symptoms without curing, so your symptoms are only abated when you take drugs, but if you die, then obviously they make no more money. I stopped taking alendronic acid straight away and now wake every morning in the hope that there might be some improvement in my condition. Alendronic Acid. Now its probable to be loosing my teeth and I live on social security and am very afraid that my dental health has been irrevocably damaged by this drug. I was in a bad way. Energice is a vitamin infused Premium Isotonic ice bar scientifically formulated with Electrolytes, B Vitamins (B3, B5, B6, B12) and Potassium. Postmenopausal osteoporosis. Hey Ive been diagnosed with polymialgia rheumatica too i was prescribed predisolone vit d evacol and now AA Im not having any side effects from it yet but reading all of these comments Im worrying about wether I should take the alendronic acid Ive only taken two up to now but have had no problem with it yet It scares you a bit, Hi I have just been precribed alendronic acid I have not taken it yet as I have had a bad cold. My mum has been taking Alendronic Acid for many years and at 82 she is almost fully bent over. Other symptoms include numbness of the lips which are also dry and sometimes numbness in the chin. Im going to stop taking Alendronic acid. This caused the bone to shatter like glass ! They began to itch the next day, ( I took my 5th dose of medication) and they were slightly better but I called my doctor and got in To the office Friday. I wish everybody all the very best and thank you for your feedback. It can support your bones depending on how long you have taken medicine. I chose the infusions and, after two infusions, the Pagets was seen to be in remission. Really concerned as Ive never ever had bowel problems!!!! My doctor didn't mention the gastrointestinal issues when prescribing Alendronic acid and neither did she mention alternative ways of improving my situation. I dont think there is enough information from doctors/nurses to explain about Osteoporosis to patients. Make sure the spinach is cooked to get rid of the oxylates which inhibit calcium absorbtion; so cook your spinach. If you suddenly stop taking the drug, you might experience severe side effects, putting you at high risk of more bone fractures. 3 months ago 43 Replies. Ostopenia and had a high risk of a fracture. There is a Group related to these awful side effects on Facebook called Reglan Support Group (Primperan/Metoclopramide Read the devastating effects this drug has had on people taking it. Menopause in women or low testosterone levels in men, Poor nutrition such as low-intake of calcium and vitamin D, Crohns disease, celiac disease, and other inflammatory bowel conditions that affect your body in absorbing nutrients, Calcium supplements, magnesium, iron, and zinc multivitamins, Cancer medicines such as bevacizumab or thalidomide and if youre undergoing chemotherapy. Your doctor will put into consideration the lifestyle changes youve made. The hospital talking about infusions once a year but still waiting for a appointment. https://info.mhra.gov.uk/drug-analysis-profiles/dap.html?drug=./UK_EXTERNAL/NONCOMBINED/UK_NON_000837661002.zip&agency=MHRA jerky muscles. Anything more and pressure builds in my head, I feel lightheaded, my ears ring and my muscles jerk happily away by themselves. Like any other drug, alendronic acid comes with mild side effects, which affect 1 in 100 people. Maybe tomorrow I will get better direction from the physician. Stopping and seeing if the symptoms resolve for most drugs is the best way to prove a link some problems with some drugs may take time more time than you expect but will resolve but some may also be permanent. However, it usually takes 6-12 months of ongoing medication to get its full benefit. After reading the comments I will not be taking it again. I have had osteoarthritis for twenty years, and was diagnosed as as having osteopenia 7 years ago. Armed with more natural solutions which I have been taking anyway but paying more attention now. Individual bisphosphonates have different . I wanted to mention to you that Ive just watched a video by Dr Jorge Flechas, called Reverse Osteoporosis with Boron. I had to ask the doctor at hospital when I went for gluten test and results. This year the odd finger started my hands have started shaking when I am on my keyboard but for the past 3 months both hands shake. Im sure they will sound familiar. How Alendronic Acid Destroyed My Life. My advice is dont risk your health when the adverse effects are so clearly documented. I am 81 years of age. I am not hoi going to take anymore Alendronic acid tablets. Muscle pain all the time hot sweats but put that down to menapause each time going to doctors about my symptoms only to be told the good will out way the bad Iike hell did it only at the end of july I was walking minding my own business with friends in torquay on holiday 1 day into my holiday I was crossing the road &my leg broke in front of me so I sustained a femur fracture due to AA which has been confirmed twice it was the AA that has caused this I have now come off them my sweats have stopped along with the others symptoms all stopped all off most I put down to a long menapause. I have stop taking the drug and will see my GP this week to see what he recomends but after reading so many stories after taking this drug i am reluctant to conti ue taking it specially as i am taking other medications for high blood pressure, tyroid, high pressure of the eyes, high colesterol.etc. I hate taking meds and wonder if I should stop Alendronic acid. This prompted me to do more research into alendronic acid, but instead of looking up this generic term, I tried the brand name Fosamax. This was after I had in some detail again described to him how prior to a jerking episode, my muscles pulled tighter and tighter before a violent release .. he metaphorically patted me on the head and told me to go and have a massage. I take 70mg PW now for about 12 mths. The wierd thing is that none of my upper teeth seem to have been affected by it. I also are very intolerant to any meds but my doctor had at last convinced me to trythis and suffice to say I will not be taking any more. I stopped taking these tablets after 3 weeks due to pain in my legs and still have it sfter 3 weeks and hoping it will come out of my body soon. Alendronate is the drug we know as Fosamax. I have had GCA for ten years now and as the result of the last of three relapses agreed to take 3mg of predisolone for the foreseeable future. The strange thing is that as soon as I read: That is exactly the reaction I had years ago to Metoclopramide the anti sickness drug. No way am I taking another drug, and particularly not this one. One thing concerns me! This study confirms what Savers have known all along: that bisphosphonates are totally ineffective at preventing fractures. Unfortunately, Im pretty intolerant to most drugs, other than HRT, which I took for 5 years without any side effects and made me feel fantasticuntil my GP refused to prescribe them once I reached 50. I would demand one straight away. It can worsen the side effects of alendronic acid in your stomach and prevent the drug from working. It is commonly prescribed to treat patients with bone issues like osteoporosis and Paget's disease . General Warnings. Below are essential things that you should know before taking alendronic acid: Tell your doctor if you have any dental implants or any tooth issues before taking alendronic acid. But, theres not enough evidence on this claim. He said the result was impossible and after another Dexa scan Im told I have osteopenia in my hip and spine. As I sat up from the bed my head started to pound. Firstly, the potential gastric problems, secondly osteonecrosis of the jaw, and thirdly the suggestion that the quality of the bone created by the drug is not as good as normal bone. Hi This has come to light since I collapsed in the shower , after complaining of thigh bone pain for over 2 years ! Stop taking your alendronic acid yes like you I been taking AA for about 2yrs in this time I have had a dry mouth enough to think Im going to lose all my teeth at the time . Bisphosphonates such as alendronic acid help halt this process by reducing the rate of bone breakdown. Federal drug regulators and researchers say that Fosamax, a drug thats supposed to help with bone growth, is linked to this rare dental disease thats also called Dead Jaw Syndrome. Hi, my story is very similar but I only found out today that Alendronic Acid has caused my dental problems. Purity & Quality Control. If you missed a dose, take it the following morning and continue taking your next doses on your usual schedule. In particular, the men we talked to felt strongly that there is still insufficient information and awareness about the fact that osteoporosis affects men. Because of how I tend to react and my blood test results, I thought I would research the new meds first and Im now very pleased that I did. Warning to anyone who might be taking Alendronic acid 70 ml tablets for osteoporosis ! But, due to some factors, your bone mass could decrease rapidly, and your body could break down bones much faster than replacing them. I will make sure I get it. You would think that and the fact that in Canada a class action suit was brought against the manufacturers of this drug, would be enough to warrant serious alarm bells. Taking alendronic acid can help if you have, or are at risk of developing, osteoporosis. 2. Ive been reading all the posts on this forum THINK I might stop altogether does anyone else get these symptoms. Dentist now tells me my teeth are not strong enough to hold a bridge again. Below are the most common things you can do to care for your bones after you stop taking alendronic acid: You probably want to get rid of taking alendronic acid as soon as possible and do the natural way of treatment to avoid serious side effects in the future. Hi Judith But you have to read the instructions carefully. They act by inhibiting osteoclast activity and bone resorption. I have taken 2 in total. I too, was prescribed this drug as, my poor mother had developed osteoporosis very badly. Hi. While there is no cure for osteoporosis, your doctor will give you a treatment plan like taking medications and lifestyle changes. The pain has travelled to her shins since stopping it. 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Worth taking if no quality of life seven weeks, the worst of my and! To have the same side effects, which affect 1 in 100 people throughout life hope are... Similar but I just couldnt describe it as I have been on 70mg. Jaw bone a year but still having problems so was referred for COLONOSCOPY!!!!!. 6-12 months of ongoing medication to get an updated dexa to see if apply. Play golf dance swim walk, so I was having an epileptic fit, but I intrigued!